Basic Principles
The Karl Fischer reaction involves:
- H₂O + I₂ + SO₂ + CH₃OH + 3RN → [RNH]SO₄CH₃ + 2[RNH]I
- Stoichiometry: 1 mol I₂ ≡ 1 mol H₂O
- Endpoint detection by voltage/current
- Precise reagent standardization
Precise Water Content Determination
ChemistryCalculatorHub.info
Calculate KF reagent titer using water standards.
Calculate sample water content using KF titration results.
Calculate drift-corrected water content.
The Karl Fischer reaction involves:
Two main methods:
Key factors for accurate results:
Common uses include:
Titer = (m × w%) / (V × 100)
Where:
m = Standard mass (g)
w% = Water content (%)
V = Titrant volume (mL)
H₂O% = (V × T × 100) / m
Where:
V = Titrant volume (mL)
T = Titer (mg/mL)
m = Sample mass (mg)
Corrected = Result - (Drift × Time)
Where:
Drift = µg H₂O/min
Time = Minutes